Weight loss drug, as its name implies is that the drug has a role in weight loss. At present, our products occupy the main market is sibutramine and orlistat two slimming products, which would give rise to varying degrees of adverse reactions. Sibutramine may lead to a rise in blood pressure, pulse, as well as to speed up significantly abnormal electrocardiogram, and so on. It should be noted that sibutramine with grapefruit juice at the same time taking, possible reactions with each other, very dangerous. Orlistat may cause gastrointestinal reactions, such as oily spots, the number of gastrointestinal exhaust, it is urgent, it oily, fatty diarrhea, increased frequency of defecation, such as fecal incontinence. In addition, orlistat also affect the body's absorption of fat-soluble vitamins, they should pay attention to the use of vitamin A, D, K and β-carotene. Slimming products are mostly prescription drugs, doctors should be able to take a decision, do not use without permission; not long-term use to prevent addiction; the two products can not be used at the same time.
[Edit this paragraph] weight loss drugs
First, loss of appetite suppression drugs
1. Amphetamine and its analogs, including amphetamine-A, benzyl amphetamine-A, non-la-an-right-and amphetamine-n, and so on, through the excitement of the nervous system, inhibiting feeding behavior, to reduce food intake and weight loss. For such a simple obesity drug better, but more side effects.
2. Fenfluramine and dexfenfluramine and its compound preparation. A number of studies confirm that these drugs can be caused heart valve damage, pulmonary hypertension and necrosis of the fingers, and other serious adverse reactions, in 1997, FDA decided to ban the use of.
3. Indole and its derivatives, such as the right indole ring and imidazole indole, such as the 1997 FDA approval of sibutramine (sibutramine) have such a role. A large number of clinical trials showed that the drug can increase the rate of fat metabolism 18-fold to heat in the form of "burning" excess fat; to reduce hunger at the same time, effective control of caloric intake. However, the drug may or high blood pressure, cardiovascular disease should be used with caution in patients with obesity.
4. Peptide and its bio-agonists or inhibitors of such drugs to be studied further.
Second, the increase in energy consumption of drugs
5. Central stimulant ephedrine, theophylline, caffeine, and so be able to stimulate fat oxidation, increased energy consumption, reduce appetite.
6. BRL26830A, BRL28410, BRL35135A make BRL37344 and adipose tissue function and metabolism in the body activated, reducing body weight; does not affect food consumption; does not affect blood sugar level. So this kind of compounds, including obesity, type 2 diabetes are obesity, many of the promising drug treatment. ICI198157 and its derivatives ICID7144 is a heat agent, a small adverse reactions. Such drugs are still in the laboratory.
7. Hormones can be low-dose hormone T3 (such as 60μg d-1) treatment of obesity, when the body does not break down the proteins increase. Growth hormone to certain types of fat have a good effect. Insulin-like growth factor (IGF1) can lead to obesity and lack of mild hyperlipidemia, genetic engineering of synthetic IGF50 ~ 150μg/kg/d long-term use can be significantly reduced in patients with subcutaneous fat content and lower serum total cholesterol, weight gain .
Third, inhibition of intestinal digestion and absorption of drugs
8. Lipase inhibitor orlistat (orlistat) can inhibit lipase, to prevent decomposition of fat molecules, thereby reducing the absorption of fat. The drug can significantly reduce blood lipids in patients with obesity. However, such drugs can lead to gastrointestinal disorders, respiratory tract infection, headache, menstrual disorders, anxiety, fatigue and so easy, but also affect the absorption of fat-soluble vitamin, resulting in a lack of fat-soluble vitamin, it should be noted that the long-term application of the appropriate fat-soluble vitamin supplement .
9. Acarbose reduced postprandial plasma glucose and insulin levels, which can cause intestinal flatulence, abdominal pain, diarrhea and so on, individual patients can respond出现低血糖.
Third, Chinese herbal medicine and its compound preparation
10. With regard to prescription medicine and a lot of reports, such as: Liu tea, Ilex, the Senate Shu powder weight loss (dangshen, Tubie insects, such as Alisma), weight loss Fujitsu granules (cassia, honeysuckle, etc.), lotus leaf Mixture, Dayan slimming tea, pollen, light capsule Kin (lotus leaf, Pinellia, Alisma, Astragalus, etc.), fat-ping (such as Pueraria lobata), Kin-fat light music, wind-San San, berberine, have There are different levels of blood fat and lose weight.
Fourth, Li Ports thin capsule drug
11. Li Ports on the thin systemic capsule used in many weight loss oriented technology, rich in natural plant extract-cream can penetrate deep, sustained release of the full fat-activated enzyme activity and rapid decomposition of the body excess fat. Force for fat burning aerobic exercise and eventually into free fatty acids, in vitro ruled out, so that the body weight fast disappearing. Its active substances are effective to prevent the accumulation of fat in the second, to stimulate the growth of elastic fibers, connective tissue to re-tighten up the slack skin, the skin to restore the original flexibility, inhibit the full rebound.
Fifth, the treatment of other obesity drugs
12. Insulin sensitizer insulin sensitizer may have insulin resistance in obese patients must have a role in weight loss. Such as rosiglitazone (rosiglitrazone), ciglitazone (ciglitazone), pag rosiglitazone (pioglitrazone), troglitazone (troglitazone), as well, such as metformin, the obese patients with diabetes and patients with simple obesity have Auxiliary role in weight loss. However, troglitazone can be caused by liver failure, death, is now suspended.
In short, the range of drug treatment of obesity, the role of different characteristics, but in recent years, the United States FDA has approved only two slimming products market, that is, orlistat and sibutramine. The current international set of uniform principles of weight loss, that is, no appetite suppressants, do not cause diarrhea, weight loss and not to reduce physical. As a result, the formulation of unified standards of efficacy, low toxicity of the search for effective weight loss drug, is the direction of future research.
[Edit this paragraph] how to choose a weight loss drug
First of all, to choose products according to their physical circumstances (such as the kind of adverse drug reactions that they have no other diseases, their body weight, etc.) have a full understanding of their own if the situation can not be identified, should consult experts or professional People should not jump to any judgments on their own. In general, the choice of weight loss products should pay attention to the following questions:
1, a clear statement on the mechanism of weight loss drugs mechanism to ensure the effectiveness of security;
2, a certificate to see whether the product has been made in the State Ministry of Health issued by the relevant quality certificates, certificates of product quality assurance;
3, the product first hit the consultation hotline advice about specific products, to investigate and try to find out at the same time listen to his views;
4, should pay attention to products Lot approval of the text, whether the country is a lot Yao Zhunzi countries such as the authority of the authorities to approve the trial. In general, the state trial of the audit requirements institutions than the local authorities strict examination and approval, by national authorities to approve the trial of the product, quality and safety are more reliable.
5, as far as possible to choose a number of major brands brand, large factories, the overall strength of a strong, well-targeted product development, advanced technology, quality, of course, also has high security, and better after-sales service.
In short, the purchase of these products should be multi-thoughtful, so that weight loss will feel at ease, also known as the heart.
[Edit this paragraph]服用减肥药-Notes
Weight loss drug for the treatment of obesity aids ---- This is a clear understanding of obesity to be a friend of common sense, or what might be called brutal truth of the obese should not be used as the main means of general only serious obesity drug when given Treatment. In theory, all kinds of weight loss drugs have side effects, long-term application of the human body can cause drug dependence and for irreversibly damaging the body. Drug caused by obesity does not change the behavior characteristics, such as diet, exercise and rest habits and environmental factors, so the choice of drug treatment should be weighing the pros and cons.
1. Weight loss drug use must be strictly indications, which use what is the best medicine under the guidance of specialists in the treatment. Any of the following conditions should be patient服用减肥药
(1) First of all, you use the formula above their ideal body weight (weight), and their actual weight compared to see if they are really obese, which is only normal body weight is more than 20% or more The real balance of fat. The reason why this issue would be highlighted is that we see, today's popular slim figure, people's minds was the ideal body weight was reduced to unrealistic, fashion model has a body like many young women to pursue. So, unless you really fat, not too much else on a diet, do not rely on medication to lose weight. Only moderate to severe obesity, that is, more than 30% overweight, can in the Treatment of diet and exercise at the same time服用减肥药treatment.
(2) obesity patients undergo strict diet control and exercise therapy, effective the beginning. However, for various reasons, patients can not be maintained, and cause weight rebound. At this time, taking some of the treatment with drugs is wise.
(3) suffering from peptic ulcer some of obesity, diet for the treatment of difficult to control, plus some drug use.
(4) to carry out a number of diet and physical activity, body weight decreased to some extent, but six months after the increase in weight once again. At this time can be服用减肥药.
(5) the methods used diet to lose weight losers, you can服用减肥药treatment.
The principle of slimming products
Weight loss of friends to know that some of the diet pills, diet tea, diet food to lose weight, its principles are to stimulate the central nervous system and reduce food intake, inhibiting diet to achieve weight loss, such as improper use can cause liver damage, endocrine disorders , And other consequences. Hormone drugs is to promote decomposition and protein metabolism in the human body and to increase consumption and achieve the purpose of weight loss: laxative and diuretic, and is by increasing the excretion of forced row to the normal human body fluids, rather than excess fat, often caused by dehydration; food to lose weight by Not digest the plant fiber, after taking a sense of satiety.服用减肥药people tend to think that after subtracting the fat is, in fact, minus the component also includes water and protein and so on, and some obvious side effects of poor results, and accompanied by relaxing the skin, rough, more wrinkles, less water The body will be added soon. So that the protein, less muscle function decline. When they stop taking drugs to lose weight, fat rapidly accumulated (rebound), the loss of muscle has not been restored. Experts warned us:服用减肥药must be combined with diet and exercise to lose weight in order to achieve the best results.
Chijianfeiyao when the taboo issues
"Eat a diet drug sibutramine, do not drink grapefruit juice, or may cause strong side effects." From the Chinese bio-pharmaceutical products registered by the experts pointed out that the weight loss drugs often lead to adverse reactions, the public should be careful .
Weight loss has become a fashion, but that only fat men over 25% of body weight, fat women more than 30% of the weight when it is called obesity. Experts suggested that the public should be controlled through diet, weight loss to strengthening the movement, and if we insist on only 3 months to reduce body weight less than 10% of the consideration will be given drugs to lose weight.
At present, to occupy slimming products market is sibutramine and orlistat two slimming products, which would give rise to varying degrees of adverse reactions.
Sibutramine may lead to a rise in blood pressure, pulse, as well as to speed up significantly abnormal electrocardiogram, and so on. It should be noted that sibutramine with grapefruit juice at the same time taking, possible reactions with each other, very dangerous.
Orlistat may cause gastrointestinal reactions, such as oily spots, the number of gastrointestinal exhaust, it is urgent, it oily, fatty diarrhea, increased frequency of defecation, such as fecal incontinence. In addition, orlistat also affect the body's absorption of fat-soluble vitamins, they should pay attention to the use of vitamin A, D, K and β-carotene.
Experts point out that slimming products are mostly prescription drugs, doctors should be able to take a decision, do not use without permission; not long-term use to prevent addiction; the two products can not be used at the same time.
[Edit this paragraph] nine Chijianfeiyao Notes
Weight loss drug for the treatment of obesity aids ---- This is a clear understanding of obesity to be a friend of common sense, or what might be called brutal truth of the obese should not be used as the main means of general only serious obesity drug when given Treatment. In theory, all kinds of weight loss drugs have side effects, long-term application of the human body can cause drug dependence and for irreversibly damaging the body. Drug caused by obesity does not change the behavior characteristics, such as diet, exercise and rest habits and environmental factors, so the choice of drug treatment should be weighing the pros and cons.
1. Weight loss drug use must be strictly indications, which use what is the best medicine under the guidance of specialists in the treatment. Any of the following conditions should be patient服用减肥药:
(1) First of all, you use the formula above their ideal body weight (weight), and their actual weight compared to see if they are really obese, which is only normal body weight is more than 20% or more The real balance of fat. The reason why this issue would be highlighted is that we see, today's popular slim figure, people's minds was the ideal body weight was reduced to unrealistic, fashion model has a body like many young women to pursue. So, unless you really fat, not too much else on a diet, do not rely on medication to lose weight. Only moderate to severe obesity, that is, more than 30% overweight, can in the Treatment of diet and exercise at the same time服用减肥药treatment.
(2) of the obese patients undergo strict diet control and exercise therapy, effective the beginning. However, for various reasons, patients can not be maintained, and cause weight rebound. At this time, taking some of the treatment with drugs is wise.
(3) suffering from peptic ulcer some of obesity, diet for the treatment of difficult to control, plus some drug use.
(4) to carry out a number of diet and physical activity, body weight decreased to some extent, but six months after the increase in weight once again. At this time can be服用减肥药.
(5) the methods used diet to lose weight losers, you can服用减肥药treatment.
2. The choice of drugs
Over the years, countries in the world for the weight loss drug research and development funding of up to billions of dollars, the market appears to lose weight is also a wide variety of drugs, such as cattle, in particular, is the official in China's market of slimming products to more than 90 . In the face of these many of these products, consumers often dazzling, I do not know how the hobby, so often the "go along with advertising." However, some weight loss products often exaggerated advertising propaganda to mislead consumers, even consumers could not eat for a few months of slimming products of the mechanism of what it is. It is worth mentioning that reduce the weight of a number of factors. What we need is the consumption of fat, not muscle, the loss of water. At present, there are many products on the market in the advertising, that the week can reduce the number of how many, should not blind faith in these ads, some drugs may contain diuretics or catharsis agent, a short period of time may alleviate some of your body weight, but the loss of water and electrolyte . You may feel dizziness, dry mouth, weak. And these drugs to "slim down" effect did not last. Weight loss drugs to lose weight on the choice of the efficacy and safety are critical. Due to a number of previously popular foreign appetite inhibitors such as fenfluramine, and so on are very serious heart complications, it is currently in the United States has been disabled. So obesity Those who need to lose weight when they find out all kinds of drug ingredients and the role of the principle of the market now compared with those "magic" weight loss products, we must hold ourselves responsible for the health of the consumer attitude clearly.
3. Use the time
Loss of appetite inhibitors can be used for adult obesity and selected obese adolescents. In the application of the restrictions on diet, exercise and behavioral therapy had not yet fully effective, they can choose to use these drugs. Loss of appetite suppression drugs can reduce hunger, reduce weight quickly. In the combined treatment, or if the dose has been adjusted to use the maximum tolerated dose of the drug suppression of appetite and weight up to 3-4 weeks has not significantly reduced, they should stop this kind of drug treatment; If you continue to reduce weight may be re - The continued application of a certain period of time.
4. The duration of drug use
Some have argued that drugs can suppress appetite in the diet, such as ineffective when short-term applications, others argue that the drugs can suppress appetite longer period of time, in order to maintain the weight loss effect to prevent the pick-up in weight.
5. Combination
Most effective weight loss drugs have varying degrees of adverse reactions, high-dose applications, in particular vulnerable. Will be a different mechanism of action of the drug combination can enhance the effect of weight loss and reduce the amount of drugs to reduce the incidence of adverse reactions. For example, loss of appetite suppression drugs fenfluramine and n-sharing, as a result of their feeding behavior of different mechanisms, the former by enhancing 5-HT system, which by enhancing the role of catecholamines have a loss of appetite suppression. The two combined to reduce the drug dose, but enhance the inhibitory effect of appetite, weight loss effects of which no less than the full amount of any of the applications, while reducing side effects. Long-term earthworm stamp it can lead to hyperinsulinemia, the effect of lowering long-term use, if the combination of insulin sensitizer, such as troglitazone, such as metformin
You can correct the adverse effects of earthworm stamp, to enhance efficacy. Chinese diet pills with low-dose combination drugs inhibit appetite films such as rhubarb and low-dose fenfluramine combined 10-20mg daily, can reduce the incidence of adverse reactions, can reach a good weight loss.
6. Special treatment groups
Young people are at a stage of growth and development of its weight loss treatment of essential drugs in order to undergo a rigorous screening and necessary to carry out strict drug custody. There are studies that, fenfluramine, you'd earthworm, growth hormone and low dose of thyroid hormone treatment of childhood obesity in general do not affect the growth and development. During pregnancy and breast-feeding banned appetite inhibitor, as a result of which may affect fetal development and growth of young children, and other weight loss drugs are not recommended. In those with heart disease, high blood pressure or fatty liver of obesity drugs to lose weight when they choose must be careful.
7. Adverse reactions and drug selection
Must understand that all drugs have some side effects, so do not blind themselves to take, take a look at the best doctors, under the guidance of doctors in using them, so safer and better able to be effective. In order to avoid adverse reactions, in general should begin taking small dose and gradually increase the volume, a guide to find the one hand and effectively lose weight, there is no significant side effects of the appropriate dose.
The vast majority of appetite suppression drugs to increase energy expenditure and weight loss drugs can have different levels of the central nervous system stimulant, showing bowel symptoms, insomnia, euphoria, and so on. Susceptibility and long-term drug dependence can occur, resulting in abuse, drug addicts and all of a sudden there will be withdrawal symptoms, particularly amphetamine addiction easy, so amphetamine and amphetamine-containing compound agents may not be used for weight loss, and also other vulnerable Have to rely on appetite suppression of amphetamine-type drugs such as amphetamine should be taken only as a second-line drugs used for weight loss. A major role fenfluramine adverse reactions mainly sedation, can cause depression, high dose can be excited to have a role in long-term drug use after a sudden stop can cause severe depression, so using this product can not be stopped treatment approach Administration. Inhibitor to increase appetite and energy expenditure of the central stimulant, thyroid hormone, and so on, through the sympathetic nervous system can generate excitement dry mouth, dilated pupils, blurred vision, dizziness, tachycardia, hypertension, cardiac arrhythmia. Sweating, and so on, the high blood pressure, angina, in patients with hyperthyroidism should not be applied. You'd use the earthworm and the common dose of fenfluramine these adverse reactions occurred in a lower rate. Patients in the general application of the above-mentioned weight loss diet pills appear clear when accompanied by a drop in blood pressure, may be susceptible to hypertension and tachycardia occurred. The use of lipase inhibitor celecoxib and glucose enzyme inhibitors, such as gastrointestinal reactions such as abdominal distension more, more, such as exhaust, which can also affect the absorption of fat-soluble vitamin, it should be long-term care.
8. Drug interactions
In theory, most of the drugs can suppress appetite caused by high blood pressure and blood pressure effects of drugs. However, the amount of common appetite inhibitor blood pressure drugs in general the role of non-interference with obvious clinical significance. Nevertheless, in the treatment of the initial 4-6 weeks should week to monitor blood pressure. Loss of appetite suppression drugs and monoamine oxidase inhibitor combination, can lead to high blood pressure crisis, the application within 2 weeks any monoamine oxidase inhibitors in patients with the banned appetite inhibitor.
9. In the course of the drug, it is necessary to pay attention to monitoring.
Before taking medication and testing must be weight and blood sugar, blood lipid, and other biochemical markers. Based on these indicators, the adjustment of drug dosage. Once the medication, do not stop at random, this may result in weight or does not rebound, should gradually increase the amount until the withdrawal. Specific practices should be conducted under the guidance of doctors.
[Edit this paragraph] slimming products, some of the elements of traditional Chinese medicine:
Cassia detoxification Qinggan
Tixu not suitable for obesity cassia Qinggan eyesight, but the health of people cold, so cold Cassia will increase, causing diarrhea, Cold. If you are a physical puffiness, cassia is not for you, you may add to the dyspepsia, indecomposable not only fat but also the extension of food storage in the body.
Lotus leaf diuretic lipid-lowering
Not suitable for visceral obesity visceral obesity refers to the subcutaneous fat is not a lot, but the surface of visceral fat has accumulated a great deal, such as diabetes, fatty liver and internal organs which are related to obesity. Lotus leaves have a good diuretic effect, can be fiery fall of the Qing fat, but if you belong to the visceral obesity, the purge of the lotus leaf on the diuretic may not be suitable for you. Take for example diabetes, the Diabetes itself is easy, urine, and urine taken to speed up the metabolism of the lotus leaf, which is tantamount to worse.
Semen Raphani purge Firming
Not suitable for muscle-fat Semen Raphani if used in the treatment of simple constipation or a bad effect on, but if you are a muscle-fat, the inappropriate nature of the purge. Muscle-fat obesity are more compact, but if Semen Raphani long-term use will result in diarrhea, dehydration and even, so that fat only to relax and not be reduced, but the area looks bigger.
Reduce Pathogenic Fire honeysuckle Qushi
Not suitable for endocrine disorder-obesity ate more than some people, but a lot of fat, which is endocrine disorder caused by obesity. In general this type of obesity is due to the weak spleen and stomach, caused by the lack of coordination, so if the prescription diet contains elements of honeysuckle, it is likely to exacerbate this lack of coordination. Honeysuckle can be reduced anger, Qushi gas, but weak stomach for those who do not fit, will add to the symptoms. So-endocrine disorder of obesity, but honeysuckle would run counter to the way you lose weight
Weight loss drugs in harmful ingredients
Diet pills are popular ways to lose weight, the market can see there are a range of range of slimming products, but some diet pills contain the following number of harmful ingredients, to arouse your attention.
Laxative:
If weight loss drugs containing laxative ingredients, there are cases of diarrhea occur, is to reduce appetite, stop taking it as long as the pick-up in weight, in addition to the regular use will damage the gastrointestinal functions, will also relax the intestines, and anemia.
[Edit this paragraph] weight loss drug banned in the three components of presentation
A lot of weight loss drug dealers in their advertising, to highlight strongly slimming products have a very magical effect of weight loss. To remind consumers, the more magic weight loss drug, the more questionable its quality, because many diet pills contain diuretics, laxatives, loss of appetite inhibitors such as 3 large components of contraband.
Diuretics: The composition is the use of "dehydration" to make the weight for the time being dropped, after the closure would obvious increase in weight, may also be accompanied by vomiting, dizziness, weakness or electrolyte imbalance, and other symptoms, such as Hydrochlorothiazide belongs to the diuretic Agent, after taking on blood lipid and blood sugar metabolism have a negative impact.
Laxative: the slimming products containing laxative by diarrhea, loss of appetite to lose weight, stop taking after the rapid weight will "bounce." If taken regularly, with the exception of intestinal injury may also lead to intestinal relaxation, such as anemia.
Loss of appetite inhibitors: this type of diet pills is a major role in the nerve center for appetite suppression, which has played anti-obesity, such as sibutramine contain ingredients that can cause high blood pressure, heart rate to accelerate, and so on.
As a result, we do not recommend the adoption of the drugs to lose weight, if you are服用减肥药, any statement need to pay attention to more than 3 kinds of prohibited elements, so as not to cause any injury.
[Edit this paragraph] all kinds of side effects of slimming products
Female beauty of the weight loss is a warm summer temperatures rose. According to the reporter visited learned that much of the weight loss drug on the market less than three, 40 kinds, and Chijianfeiyao accident reports frequently seen in newspapers. These products of their ads really said, it can be quickly and effectively shape the Monster build it? Reporters will visit a special report of the experts are as follows. ?
Kang Ting capsule, Jane Hall Health benefits of thin film, the line of slimming capsules, weight loss boke music, Victoria Pavilion, V26 sand grain weight loss, the magic fish of thin film
The main ingredients: L-carnitine, which is the body's metabolism of essential "vitamins" of nutrients.
Side-effects: According to experts, as a nutritional additive itself has no side-effects of these drugs to lose weight, but if you take this way to lose weight, long-term use may cause physical harm, the human body every day because of the need for a comprehensive, balanced and adequate diet, mineral water Compounds, protein, fat, like Less, eat vitamin-ray is likely to cause malnutrition.
US-song, show, the United States and Connaught-ting
The main ingredient: Sibutramine side effects: weight loss drug experts believe that the role is to enhance satiety, reduce energy intake and promote muscle and adipose tissue glucose utilization, reduce blood sugar, blood lipid. The composition and fenfluramine similar with addiction.
Xenical
The main ingredient: orlistat side effects: experts point out that this component may reduce the absorption of fat-soluble fat, suppress appetite and resist the use of fat may lead to drug use were not sufficient to absorb nutrients, leading to a serious lack of potassium such as mine Material, rapid heart beat, emerged.
Yu Chi-tang capsule to lose weight, light-Tang Qing-fat, slimming month of the new hall, Doyle, Austria Yun, Bao Tong, the United States treasure
The main components: Emodin side: the side effects of traditional Chinese medicine experts believe that smaller, but research shows that long-term use of emodin may have a kidney injury. Yu Chi-tang was investigated and dealt with after the discovery of which contain banned in China fenfluramine, which, as Yu Chi-tang of Chinese slimming capsules did not say.
According to the experts said, there are a lot of weight in Chinese medicine practice to add a western medicine.
[Edit this paragraph] to avoid weight loss drug weight loss methods
First, weight loss campaign. In fact, a simple exercise to lose weight the results have been very limited in movement should take appropriate pre-L-carnitine to speed up the consumption of fat, so to do to lose weight. The advantage of less costly, and many of the shortcomings is not easy to adhere to the campaign.
Second, on behalf of meals to lose weight. Eat three meals a day after a special formula designed by controlling energy intake to lose weight. Without the advantage of the security side, on behalf of the disadvantage is that weight loss meal flour taste often monotonous.
Third, to lose weight equipment. Results are usually open to doubt.
减肥药，顾名思义就是具有减肥作用的药物。目前占据我国减肥药市场的主要是西布曲明和奥利司他两种减肥药,它们都会引起不同程度的不良反应。 西布曲明可能导致血压上升、脉搏明显加快以及心电图异常等。值得注意的是，西布曲明如果与西柚汁同时服用，可能发生相互反应，十分危险。奥利司他可能引起胃肠道反应，如油性斑点、肠胃排气增多、便急、油状便、脂肪泻、排便次数增多、大便失禁等。此外，奥利司他还会影响人体对脂溶性维生素的吸收，使用时应注意补充维生素A、D、K和β-胡萝卜素。减肥药多属处方药，能否服用应由医生决定，不要擅自服用；不要长期使用，以免成瘾；两种减肥药也不能同时使用。
[编辑本段]减肥药物种类
一、食欲抑制药
1. 苯丙胺及其类似物,包括甲苯丙胺、苄甲苯丙胺、安非拉酮、右苯丙胺和苯丁胺等,可通过神经系统的兴奋作用,抑制觅食行为,减少食物摄入,减轻体重。此类药物对于单纯性肥胖症效果较好,但不良反应较多。
2. 芬氟拉明、右芬氟拉明及其复方制剂。多项研究证实,此类药物可致心脏瓣膜损害、肺动脉高压和手指坏死等严重不良反应,于1997年,ＦＤＡ决定禁止使用。
3. 吲哚类及其衍生物,如吗吲哚及环咪唑吲哚,如1997年ＦＤＡ批准的西布曲明(sibutramine)具有此类作用。大量临床试验表明,此药能使脂肪代谢速度增加18倍,以产热的形式“燃烧”多余脂肪;同时减少饥饿感,有效控制热量摄入。但该药可升高血压,有心血管疾病的肥胖患者应慎用。
4. 生物肽类及其激动剂或抑制剂 此类药尚待进一步研究。
二、增加能量消耗的药物
5. 中枢兴奋药 麻黄碱、茶碱、咖啡因等能刺激脂肪氧化、增加能量消耗,也可减少食欲。
6. ＢＲＬ26830Ａ,ＢＲＬ28410,ＢＲＬ35135Ａ和ＢＲＬ37344使脂肪组织的功能和全身代谢活化,体重减少;不影响摄食量;不影响血糖值。所以这类化合物对包括肥胖型糖尿病在内的很多肥胖都是有希望的治疗药。ＩＣＩ198157及其衍生物ＩＣＩＤ7144是一个产热剂，不良反应很小。此类药尚在实验室中。
7. 激素类 可采用低剂量甲状腺素T3(如60μｇ·ｄ-1)治疗肥胖,此时机体蛋白质的分解并不增加。生长激素对某些类型的肥胖有很好的疗效。胰岛素样生长因子(IGF1)缺乏可导致肥胖及轻度高血脂症,用基因工程合成的IGF50～150μｇ/kg/d长期服用,可显著减少患者皮下脂肪的含量,降低血清总胆固醇,但体重增加。
三、抑制肠道消化吸收的药物
8. 脂肪酶抑制剂 奥利司他(orlistat)可抑制脂肪酶,阻止脂肪分子分解,从而减少脂肪的吸收。该药尚可明显降低肥胖患者血脂。但该类药物可导致胃肠道功能紊乱、呼吸道感染、头痛、月经失调、焦虑、易疲劳等,还影响脂溶性维生素的吸收,造成脂溶性维生素缺乏,故长期应用应注意适当补充脂溶性维生素。
9. 阿卡波糖降低餐后血糖及血浆胰岛素水平，但可引起肠胀气、腹痛、腹泻等,个别患者还可出现低血糖反应。
三、中草药及其复方制剂
10. 关于中药及方剂的报道很多,例如:柳茶、苦丁茶、参庶减肥粉(党参、土鳖虫、泽泻等)、富士减肥冲剂(决明子、金银花等)、荷叶合剂、大雁减肥茶、花粉、轻健胶囊(荷叶、半夏、泽泻、黄芪等)、去脂平(葛根等)、轻身健脂乐、防风通圣散、黄连素等,都有不同程度的降血脂与减轻体重的作用。
四、俪宝姿瘦身胶囊药物
11.关于俪宝姿瘦身胶囊采用全身多处定向减肥技术，富含萃取天然植物精华素，可深度渗透、持续释放、全面激活脂肪酶活性、快速分解体内多余脂肪。迫使脂肪进行有氧燃烧运动，最终转变为游离脂肪酸，排除体外，令体内赘肉快速消失。其活性物质能有效阻止脂肪的二次堆积，刺激弹性纤维生长，令结缔组织重新组合，收紧松弛的肌肤，恢复皮肤原有弹性，全面抑制反弹。
五、其他治疗肥胖的药物
12. 胰岛素增敏剂胰岛素增敏剂可能对具有胰岛素抵抗的肥胖患者产生一定减肥作用。如罗格列酮(rosiglitrazone)、噻格列酮（ciglitazone）、帕格列酮（pioglitrazone）、曲格列酮（troglitazone）以及二甲双胍等,对伴有糖尿病的肥胖患者及单纯性肥胖患者均有辅助减肥作用。但曲格列酮可致肝衰竭、死亡,现已停用。
总之,肥胖症的治疗药物琳琅满目,各有不同作用特点,但近年来,美国ＦＤＡ只批准两个减肥药上市,即奥利司他和西布曲明。现今国际上制定了统一的减肥原则,即不抑制食欲、不引起腹泻、减轻体重而不降低体力。因此,制订统一的疗效标准,寻找高效低毒的减肥药,是今后研究的方向。
[编辑本段]如何选择减肥药物
选择减肥药首先要根据自己的身体素质情况（例如对那种药物产生不良反应，自己有没有其它疾病，自己的体重等）有个全面了解，如果自己对情况不能确定的话，应请教专家或专业人士，不要自行妄下判断。 一般来说，选择减肥产品应注意以下几个问题：
1、机理 看清说明书上药物的减肥机理，确保安全有效性；
2、证书 看产品是否已取得国家卫生部颁发的相关品质证书，有证书的产品质量有保证；
3、咨询 先打该产品的热线电话咨询一下产品的具体情况，调查了解清楚，同时听取同伴的意见；
4、 批号 要注意产品批准文号，是否是国药准字批号等国家权威主审机关审批。一般来说，国家主审机关的审核要求比地方审批机关严格，能够通过国家主审机关审批的产品，品质与安全性都较为可靠。
5、品牌 尽可能选择一些大品牌，大厂家整体实力强大，产品发展目标明确，技术力量先进，质量当然也有很高的保障，且售后服务较为完善。
总之，购买减肥产品时应多方考虑周全，这样减肥才会安心又称心。
[编辑本段]服用减肥药物注意事项
药物减肥为肥胖治疗的辅助手段----这是肥胖朋友必须认清的常识,或者可称为残酷真相，肥胖者不应以此作为主要手段，一般只 在严重的肥胖症时再给予药物治疗。从理论上讲各种减肥药都有不良反应，长期应用会造成人体对药物的依赖性和对身体造成不可挽回的损害。药物并不能改变造成肥胖的行为特征如饮食习惯,运动锻炼,作息习惯等及环境因素等，因此在选择药物治疗时应权衡利弊。
1.用减肥药物一定要严格掌握适应症，哪些人使用何种药物最好是在专科医生的指导下进行治疗。凡有下列情况的病人应服用减肥药
（1）首先，你用上面讲到的公式计算出自己的理想体重（标准体重），再和自己的实际体重比较一下，看看自己是否真的肥胖，只有哪些体重超过正常20%以上的人才算真正的肥胖。之所以把这一点着重指出是我们看到，再流行苗条身段的今天，人们心中理想体重被被不切实际地减轻了，拥有时装模特儿般地身材成为许多年轻女性地追求。所以，除非你真的肥胖，否则就不要过分节食，更不要靠吃药来减肥。只有中重度肥胖，即超重30%以上者，才可以在饮食和运动治疗的同时服用减肥药治疗。
（2）肥胖症病人，经过严格的饮食控制和运动治疗，开始有效。但由于种种原因，病人无法坚持下去，而且造成体重反弹。这时，服用一些药物配合治疗是明智的。
（3）某些患有消化性溃疡的肥胖者，进行饮食治疗控制有困难，可加用一些药物。
（4）一些人进行饮食控制和体育锻炼后，体重得到一定程度的下降，但半年后体重又重新上升。这时可服用减肥药。
（5）用节食的方法减肥失败者，可以服用减肥药治疗。
减肥药的原理
减肥的朋友要知道，一些减肥药，减肥茶，减肥食品的减肥作用，其原理多是刺激中枢神经系统，减少摄入食品，抑制饮食达到减肥，如用药不当，会造成肝脏损伤，内分泌失调等后果。激素类药物是促进人体代谢和蛋白质分解并增加消耗而达到减轻体重的目的：而泻药和利尿剂是通过增加排泄，强行排去人体正常体液，而非多余脂肪，常造成脱水；食品减肥多由不宜消化的植物纤维组成，服用后有饱感。服用减肥药后人们往往认为减去的是脂肪，其实减去的成分中还包括水分和蛋白质等，而且有的副作用明显成效不佳，并伴随出现皮肤松弛，粗糙，皱纹增多，减去的水分身体会很快补充。减去蛋白质使肌肉机能下降。当停止服用这些减肥药物后，脂肪会迅速积累起来(反弹)，而失去的肌肉却未得到恢复。专家告诫我们：服用减肥药必须结合节食，运动方可达到最佳的减肥效果。
吃减肥药时的禁忌事项
“吃了减肥药西布曲明，千万不能喝西柚汁，否则可能引起强烈的不良反应。”来自中国药品生物制品检定所的 专家 日前指出， 药物 减肥往往导致不良反应，公众应谨慎从事。
减肥已经成为时尚，但却指出，只有男性脂肪超过体重25%、女性脂肪超过体重30%的时候才称为肥胖。专家建议，公众应先通过节制饮食、加强运动来减肥，如果坚持3个月体重只减轻了不到10%，再考虑药物减肥。
介绍，目前占据减肥药市场的主要是西布曲明和奥利司他两种减肥药，它们都会引起不同程度的不良反应。
西布曲明可能导致血压上升、脉搏明显加快以及心电图异常等。值得注意的是，西布曲明如果与西柚汁同时服用，可能发生相互反应，十分危险。
奥利司他可能引起胃肠道反应，如油性斑点、肠胃排气增多、便急、油状便、脂肪泻、排便次数增多、大便失禁等。此外，奥利司他还会影响人体对脂溶性维生素的吸收，使用时应注意补充维生素A、D、K和β-胡萝卜素。
专家指出，减肥药多属处方药，能否服用应由医生决定，不要擅自服用；不要长期使用，以免成瘾；两种减肥药也不能同时使用。
[编辑本段]吃减肥药的九个注意事项
药物减肥为肥胖治疗的辅助手段----这是肥胖朋友必须认清的常识,或者可称为残酷真相，肥胖者不应以此作为主要手段，一般只在严重的肥胖症时再给予药物治疗。从理论上讲各种减肥药都有不良反应，长期应用会造成人体对药物的依赖性和对身体造成不可挽回的损害。药物并不能改变造成肥胖的行为特征如饮食习惯,运动锻炼,作息习惯等及环境因素等，因此在选择药物治疗时应权衡利弊。
1.用减肥药物一定要严格掌握适应症，哪些人使用何种药物最好是在专科医生的指导下进行治疗。凡有下列情况的病人应服用减肥药：
（1）首先，你用上面讲到的公式计算出自己的理想体重（标准体重），再和自己的实际体重比较一下，看看自己是否真的肥胖，只有哪些体重超过正常20%以上的人才算真正的肥胖。之所以把这一点着重指出是我们看到，再流行苗条身段的今天，人们心中理想体重被被不切实际地减轻了，拥有时装模特儿般地身材成为许多年轻女性地追求。所以，除非你真的肥胖，否则就不要过分节食，更不要靠吃药来减肥。只有中重度肥胖，即超重30%以上者，才可以在饮食和运动治疗的同时服用减肥药治疗。
（2）肥胖病人，经过严格的饮食控制和运动治疗，开始有效。但由于种种原因，病人无法坚持下去，而且造成体重反弹。这时，服用一些药物配合治疗是明智的。
（3）某些患有消化性溃疡的肥胖者，进行饮食治疗控制有困难，可加用一些药物。
（4）一些人进行饮食控制和体育锻炼后，体重得到一定程度的下降，但半年后体重又重新上升。这时可服用减肥药。
（5）用节食的方法减肥失败者，可以服用减肥药治疗。
2.药物的选择
多年来，世界各国用于减肥药品研究与开发的经费高达数十亿美元，市场上出现的减肥药品也是五花八门，多如牛，尤其是目前正式在我国市场上出售的减肥产品以达90余种。面对这些层出不穷的减肥产品，消费者常常眼花缭乱，不知如何嗜好，于是往往是"跟着广告走"。可是有的减肥品广告经常夸大宣传、误导消费者，甚至连消费者也说不出吃了几个月的减肥品它的作用机理何在。值得一提的是，体重的减轻有很多因素。我们需要的是脂肪的消耗，而不是肌肉，水分的丧失。目前市面上有很多减肥药在大做广告，宣称一周内可以减轻多少多少，不要迷信这些广告，有些药物可能含有导泻剂或利尿剂，短期内可能减轻你一些体重，但失去的水分和电解质。你可能会感到头晕，口干，乏力。并且这些药物"减肥"效果并不持久。减肥的药物选择对减肥的效果和安全性非常关键.由于一些以前国外非常流行的食欲抑制剂如芬氟拉明等对心脏有很严重的并发症,所以目前在美国已被禁用.所以肥胖者减肥时必须弄清楚各种药物的成分和作用的原理,对现在市面上那些比较"神秘"的减肥品,一定要抱着对自己的健康负责的态度明明白白地消费.
3.用药时机
食欲抑制药可用于成年肥胖者及经过选择的青少年肥胖者。在应用了饮食限制、运动及行为疗法后仍未充分收效时，可以选用这类药物。食欲抑制药可使饥饿感减低，体重迅速降低。在综合治疗中，如果经调整剂量或已使用了最大耐受量的食欲抑制药达3-4周而体重仍未明显减轻，则应停止该类药物的治疗；如果体重继续降低，则可再持续应用一段时间。
4.用药的持续时间
有人主张食欲抑制药只能在饮食控制等效果不佳时短期应用，但亦有人认为食欲抑制药可以较长时间使用，以保持减肥疗效，防止体重回升。
5.联合用药
大多数有效减肥药均有不同程度的不良反应，大剂量应用时，尤其容易发生。将作用机制不同的药物合用，可以增强减肥疗效，减少药物用量，减少不良反应的发生率。例如将食欲抑制药芬氟拉明与苯丁胺合用，由于其对觅食行为的影响机制不同，前者通过增强5一羟色胺系统，后者通过增强儿茶酚胺类作用产生食欲抑制。二者合用时各药剂量减少，但食欲抑制作用增强，减肥疗效不亚于其中任何一种的足量应用，而不良反应减少。长期应用吗蚓跺可导致高胰岛素血症，故长期使用时疗效降低，若合用胰岛素增敏剂如曲格列酮、二甲双胍等
则可纠正吗蚓跺的不良影响，增强疗效。中药减肥药与小剂量食欲抑制药合用如大黄片与小剂量芬氟拉明每日10-20mg合用，可降低不良反应的发生率，亦能达到良好的减肥效果。
6.特殊人群用药
青少年正处于生长发育阶段，对其减肥的治疗必需经过严格筛选才能用药，并且必需进行严密的用药监护。有研究认为，芬氟拉明、吗蚓跺、生长激素及小剂量的甲状腺激素治疗儿童肥胖一般不影响其生长发育。妊娠期和哺乳期间禁用食欲抑制药，因可能影响胎儿发育及幼儿成长，其他减肥药也不推荐使用。在患有心脏病,高血压或者有脂肪肝的肥胖者选择减肥药时一定要慎重.
7.不良反应与选药
必须明白，凡是药物都有一定的副作用，所以不要盲目的自行服用，最好先看看医生，在医生的指导下服用，这样比较安全，也更能收效。为避免不良反应，一般应先从小剂量开始服药，逐渐加量，指导找到一个既能有效减轻体重，有不会产生明显副作用的合适剂量。
绝大多数的食欲抑制药及增加能量消耗的减肥药都可以产生不同程度的中枢神经系统兴奋作用，表现出易激惹症状、失眠、欣快感等。易感者及长期用药可发生依赖性，造成滥用，成瘾者突然停药会出现戒断症状，尤以苯丙胺易成瘾，故苯丙胺和含有苯丙胺的复合制剂不可用于减肥，其他也易产生依赖的苯丙胺类食欲抑制药如甲苯丙胺只宜作为二线药物用于减肥。芬氟拉明主要作用不良反应主要表现为镇静作用，可造成抑郁症，大剂量则可产生兴奋作用，长期用药后突然停药可造成严重的抑郁，故用本品不能以间断疗程的方式给药。食欲抑制药及增加能量消耗的中枢兴奋药、甲状腺激素等，通过兴奋交感神经系统可产生口干、瞳孔放大、视力模糊、头晕、心动过速、血压升高、心律失常。出汗等，故高血压、心绞痛、甲状腺功能亢进患者不宜应用。使用吗蚓跺及常用剂量的芬氟拉明上述不良反应的发生率较低。一般患者在应用上述减肥药出现明确体重减轻时，可以伴随着血压下降，易感者则可出现血压升高及心动过速。使用脂肪酶抑制剂及葡萄糖昔酶抑制药等胃肠道反应较多如腹胀,排气多等，前者还可影响脂溶性维生素的吸收，故长期应用应慎重。
8.药物的相互作用
从理论上说大多数食欲抑制药都能引起血压升高，并影响降压药的作用。但常用量的食欲抑制药对一般降压药作用的干扰无明显的临床意义。尽管如此，在治疗最初的4-6周内仍应每周监测血压。抑制食欲的药物与单胺氧化酶抑制剂合用，可导致高血压危象，因此2周内应用过任何单胺氧化酶抑制剂的患者禁用食欲抑制药。
9.在用药的过程中，要注意监测。
服药前和服药时必须检测体重和血糖，血脂等生化指标。根据这些指标，调整药物的剂量。一旦服药，不要随意停止，这样可能会导致不适或体重反弹，应逐渐加量，直至停药。具体做法应在医生指导下进行。
[编辑本段]减肥药里的一些中药成份：
决明子清肝排毒
不适合体虚型肥胖决明子清肝明目，但是对于体质寒凉的人来说，决明子就会让寒凉加重，引起腹泻、虚寒。如果你是虚胖体质，那么决明子就不适合你，可能会加重你的消化不良，不但不能分解脂肪，更会延长食物在体内存储的时间。
荷叶利尿降脂
不适合内脏型肥胖 内脏型肥胖指的是皮下脂肪并不很多，但是内脏表面已经堆积了大量脂肪，像糖尿病、脂肪肝这些都与内脏型肥胖有关。荷叶有很好的利尿作用，可以降火气、清脂肪，但是如果你属于内脏型肥胖，那么通便利尿的荷叶就未必适合你。就拿糖尿病来说吧，本身就容易消渴、多尿，再服用了加速小便代谢的荷叶，那无异于雪上加霜。
莱菔子通便紧肤
不适合肌肉型肥胖 莱菔子如果用在单纯的治疗便秘上效果还是不错的，但是如果你是肌肉型肥胖，这个通便的性质就不合适。肌肉型肥胖的脂肪都比较紧致，但是如果长期使用莱菔子就会造成腹泻，甚至脱水，这样一来，脂肪只会松弛，并不会减少，反而看起来面积更大了。
金银花降火祛湿
不适合内分泌紊乱型肥胖 有些人吃得不多，但还是脂肪不少，这就是内分泌紊乱造成的肥胖。一般这种类型的肥胖都是由于脾胃虚弱、不协调造成的，所以如果减肥药方中含有金银花的成分，那就很可能加剧这种不协调。金银花可以降火气、祛湿气，但是对于脾胃虚弱的人就不适合，会加重症状。所以对于内分泌紊乱型的肥胖人群，金银花反而会让你在减肥路上背道而驰
减肥药品中的有害成分
减肥药是流行的减肥方式，市场上可以见到有各式各样、琳琅满目的减肥药，可是，有些减肥药中含有下面一些对身体有害的成分，希望引起您的注意。
泻药：
减肥药品中若含有泻药成分，则会有腹泻的情形发生，使人降低食欲，只要停止服用体重会回升，经常使用除了会损伤肠胃道的功能，也会发生肠子松弛、贫血的问题。
[编辑本段]减肥药中的三种违禁成分介绍
不少减肥药的经销商在其广告宣传中，极力突出减肥药有着非常神奇的减肥效果。在此提醒消费者，越是减肥效果神奇的药物，其质量越值得怀疑，因为不少减肥药都含有利尿剂、泻药、食欲抑制剂等3大违禁成分。
利尿剂：该成分是利用“脱水”来使体重暂时下降，但停用后体重会明显上升，还可能伴有呕吐、头晕、虚弱或电解质紊乱等症状，如双氢克尿噻就属于利尿剂，服用后会对血脂、血糖代谢产生不良影响。
泻药：含有泻药的减肥药是通过腹泻、食欲减退来减轻体重，停止服用后体重会快速“反弹”。如果经常服用，除可能损伤肠道，还会导致肠松弛、贫血等。
食欲抑制剂：这类减肥药主要是作用于神经中枢来抑制食欲，从而起到减肥功效，如含有西布曲明成分的药物，还可造成血压升高、心率加快等。
因此，不建议大家通过服用药物来减肥，如果您正在服用减肥药，需留意说明书有无以上3种违禁成分，以免对身体造成伤害。
[编辑本段]各种减肥药的副作用
爱美女性的减肥热情正在盛夏的气温中上升。据记者走访了解，目前充斥于市面上的减肥药不下三、四十种，而吃减肥药发生意外的报道频频见于报端。这些减肥药真如其广告所言，可以在短期内快速、有效地塑造魔怪身材吗?记者特意将走访专家的意见报告如下。?
康丽亭胶囊、益生堂简瘦身片、金线减肥胶囊、博凯减肥乐、维亭、V26减肥沙晶、魔鱼瘦身片
主要成分：左旋肉碱，它是人体代谢的必需的“类维生素”的营养素。
副作用：据专家介绍，作为营养强化剂本身这些减肥药并无副作用，但是如果采取这种方式减肥，长期服用可能会对身体造成危害，因为人体每天需要全面、均衡、适量的饮食，矿水化合物、蛋白质、脂肪一样都不能少，光吃维生素很可能造成营养不良。
曲美、可秀、诺美婷
主要成分：西布曲明副作用：专家认为这种减肥药的作用是提高饱感，减少能量摄入，促进肌肉、脂肪组织对葡萄糖的利用，降低血糖、血脂。该成分与芬氟拉明相似，具有成瘾性。
赛尼可
主要成分：奥利司他副作用：专家指出这种成分可能会减少脂溶性脂肪的吸收，服用抑制胃口与抵挡脂肪的药物可能导致服食者无法吸收足够的营养，导致严重缺乏如钾这类矿物质，出现心跳加速的现象。
御芝堂减肥胶囊、轻身堂清脂素、纤体堂月月新、朵尔、奥韵、宝丽堂、美之宝
主要成分：大黄素副作用：专家认为中药的副作用较小，但是研究表明长期服用大黄素可能对肾脏产生伤害。御芝堂在被查处后发现其中含有我国禁止的芬氟拉明，这在作为中药的御芝堂减肥胶囊中并没有说明。
据专家透露，现在有不少减肥中药中实际上添加了西药。
[编辑本段]避免减肥药的减肥方法
一、运动减肥。其实单纯运动其减肥效果相当有限，应在运动前适量服用左旋肉碱以加快脂肪消耗，这样减肥才好。优点是花费较少，缺点是许多人不容易坚持运动。
二、代餐减肥。一日三餐食用经过特殊设计的配方食品，通过控制能量摄入来减肥的方法。优点是安全无副作用，缺点是减肥代餐粉的口味往往比较单调。
三、器械减肥。效果通常值得怀疑。
